What is ALS? Here's what's known about the neurodegenerative disease

Actor Eric Dane, known for his roles in 'Grey's Anatomy' and 'Euphoria,' has died less than a year after publicly revealing his diagnosis with ALS, or Lou Gehrig's disease, prompting CBS News contributor Dr. Celine Gounder to provide expert insights on the neurodegenerative disease during 'CBS Mornings.' ALS, or Amyotrophic Lateral Sclerosis, is a progressive neurodegenerative disease that affects nerve cells in the brain and spinal cord, leading to the loss of muscle control. Dr. Gounder explained that the disease typically affects people between the ages of 40 and 70, with men being slightly more susceptible than women. The condition gradually weakens the muscles, affecting the ability to speak, eat, move, and eventually breathe. Dane's case highlights the aggressive nature of some forms of the disease, as he passed away relatively quickly after his diagnosis. The exact cause of ALS remains unknown in most cases, though researchers have identified potential risk factors including genetics, environmental exposures, and lifestyle factors. Dr. Gounder noted that while approximately 5-10% of ALS cases are inherited, the majority occur randomly. The disease affects approximately 5,000 new people in the United States each year, with an estimated 20,000-30,000 Americans living with ALS at any given time. Despite ongoing research, there is currently no cure for ALS, and treatments focus on managing symptoms and maintaining quality of life.