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🌐 Entity
Tumour heterogeneity
Observation of the diversity of tumour cells
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📌 Topics
- Medical imaging (1)
- Artificial intelligence (1)
- Machine learning optimization (1)
🏷️ Keywords
AINet (1) · Anchor instances (1) · Whole slide image (1) · Tumor heterogeneity (1) · Multi-instance learning (1) · Medical AI (1) · Image processing (1) · Computational efficiency (1)
📖 Key Information
Tumour heterogeneity describes the observation that different tumour cells can show distinct morphological and phenotypic profiles, including cellular morphology, gene expression, metabolism, motility, proliferation, and metastatic potential. This phenomenon occurs both between tumours (inter-tumour heterogeneity) and within tumours (intra-tumour heterogeneity). A minimal level of intra-tumour heterogeneity is a simple consequence of the imperfection of DNA replication: whenever a cell (normal or cancerous) divides, a few mutations are acquired—leading to a diverse population of cancer cells.
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