🌐 Entity
Sebetralstat
Chemical compound
📊 Rating
1 news mentions · 👍 0 likes · 👎 0 dislikes
📌 Topics
- Pharmaceuticals (1)
- Stock Analysis (1)
🏷️ Keywords
Leerink (1) · Kalvista (1) · Ekterly (1) · stock rating (1) · sales (1) · pharmaceuticals (1) · investment (1)
📖 Key Information
Sebetralstat, sold under the brand name Ekterly, is a medication used for the treatment of hereditary angioedema. Sebetralstat is a plasma kallikrein inhibitor that suppresses the activation of the positive feedback mechanism of the kallikrein-kinin system, thereby reducing factor XIIa and additional plasma kallikrein production. By inhibiting plasma kallikrein, sebetralstat reduces the production of bradykinin, thereby halting the progression of hereditary angioedema attacks.
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