How much of a cancer drug do patients need? U. of C. doctor, others challenge the FDA, drugmakers on dosing.
<p>Northwestern University economist Chuck Manski studies decision-making amid uncertainty. That prepared him better than many other cancer patients to decide whether to stay on an immunotherapy treatment that was making him very ill.</p><p>For six months in 2022, Manski received monthly infusions of nivolumab to fight advanced melanoma.
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<p>Northwestern University economist Chuck Manski studies decision-making amid uncertainty. That prepared him better than many other cancer patients to decide whether to stay on an immunotherapy treatment that was making him very ill.</p><p>For six months in 2022, Manski received monthly infusions of nivolumab to fight advanced melanoma. The drug ruined his thyroid gland, he said, requiring him to go on a special medication for the rest of his life, and caused severe dryness in his eyes, lips and mouth.</p><p>The federal Food and Drug Administration’s protocol for the drug called for an entire year of treatment, but Manski said his oncologist couldn’t explain why. It’s FDA-approved, “so that’s what we use,” he said he was told.</p><p>By that point, Manski showed no cancer signs or symptoms.
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- <p>Northwestern University economist Chuck Manski studies decision-making amid uncertainty. That prepared him better than many other cancer patients to decide whether to stay on an immunotherapy treatment that was making him very ill.</p><p>For six months in 2022, Manski received monthly infusions of nivolumab to fight advanced melanoma.
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How much of a cancer drug do patients need? U. of C. doctor, others challenge the FDA, drugmakers on dosing.
Sources1TypeCoverageChicago Sun-Times